All engineering research in ATP-Bio is aimed at eliminating or mitigating the three enemies of biopreservation: ice formation, cryoprotective agent (CPA) toxicity, and slow and/or non-uniform rewarming.
1. Excessive Ice Formation
2. CPA Toxicity
3. Thermal and Mechanical Stress
CONVERGENT RESEARCH
Thrust Area 1: Biological Engineering
We aim to develop new CPAs and CPA delivery, uptake, and removal systems to reduce or eliminate CPA toxicity. This will involve engineering at the molecular, genetic/cellular, and tissue/organ levels.
Each of our testbeds connects to a distinct market segment. We aim to produce biopreservation technologies that will accelerate the growth of each of these market segments via new products and vastly improved storage and distribution of products.
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