ATP-Bio Impacts

ATP-Bio CryoClips deliver quick, engaging looks at the cutting-edge science and technology emerging from the NSF Engineering Research Center for Advanced Technologies for the Preservation of Biological Systems (ATP-Bio).

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Welcome to ATP-Bio Freeze Frames, a video series spotlighting the people driving innovation across the NSF Engineering Research Center for Advanced Technologies for the Preservation of Biological Systems (ATP-Bio).

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ATP-Bio CryoClips: Research Impact

Project 1: Organoids

Organoids are tiny, lab-grown versions of human organs that help scientists study how our bodies work and develop new medicines. With more support to make, store, and share these mini-organs, we can speed up discoveries that improve health and healthcare around the world.

Read more here: Atala, A., Bischof, J.C., Chen, C.S., Fisher, J.P., Hermanson, D.L., Howe, C.L., Low, W.C., Ma, Z., McKenna, D.H., Palecek, S.P., Temenoff, J.S., Ogle, B.M. (2025). The need for an organoid manufacturing, preservation, and distribution center. Stem Cells Translational Medicine. 14 (7), [szaf031]. DOI: https://doi.org/10.1093/stcltm/szaf031

Project 2: Pausing Biological Time

Scientists are developing new ways to “pause” biological time using cutting-edge biopreservation techniques like supercooling and vitrification. These methods could greatly extend how long donor organs remain viable outside the body — shifting organ transplants from urgent, last-minute procedures to carefully planned surgeries. This breakthrough holds the potential to not only save more lives, but also make organ distribution more fair and equitable.
As we explore these powerful technologies, it’s vital that we do so ethically  – ensuring access is guided by need, not privilege, and that advances serve the common good.

Read more here: Pruett, T.L., Wolf, S.M., McVan, C.C., Lyon, P., Capron, A.M., Childress, J.F., Evans, B.J., Finger, E.B., Hyun, I., Isasi, R., Marchant, G.E., Maynard, A.D., Oye, K.A., Toner, M., Uygun, K., Bischof, J.C. (2025). Governing new technologies that stop biological time: Preparing for prolonged biopreservation of human organs in transplantation. American Journal of Transplantation. 25 (2), [269-276]. https://www.amjtransplant.org/article/S1600-6135(24)00572-0/abstract.

ATP-Bio Freeze Frames: People Impact

Project 1: ATP-Bio Coloring Book

Did you know some animals can freeze… and still stay alive? snowflake Yep — their hearts stop beating, but they don’t die!

Welcome to the ATP-Bio Coloring Book, brought to you by the NSF ATP-Bio Center — where science, engineering, and the natural world come together in amazing ways!

"A young artist brings ATP-Bio’s science to life, filling the pages of our ATP-Bio Coloring Book with bright imagination and curiosity. Each color adds a spark of creativity to the world of cryobiology."
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