CONVERGENT RESEARCH VISION & GOALS

The overarching goal of ATP-Bio is to discover, scale up and translate the development of technologies that enable widespread preservation and distribution of cells, microphysiological systems, tissues and organs, and whole organisms, ultimately leading to profound impacts on society in areas spanning healthcare, food supply and sustainability and biodiversity. 

ATP-Bio envisions a world where a vast range of biological systems are preserved in a high throughput manner for a wide range of benefits to humankind and the natural environment.

All our preservation technologies aim to “stop biological time” by lowering the metabolism of the living systems during the preservation period. This is achieved by cooling the systems to temperatures below 0ºC and rewarming them to functional temperatures when needed. Both cooling and rewarming steps can be highly damaging to the products unless some precautions are taken to prepare the samples to undergo these wide temperature changes. Our convergent research team tackles all aspects of these challenges with a multi-disciplinary approach utilizing a wide spectrum of expertise spanning over all institutions.


Convergent Research Team

Convergent Research Leadership Team

KORKUT UYGUN (MGH)
Research Director

CATHERINE HEREMANS (MGH)
Research Program Manager

SHANNON TESSIER (MGH)
TA1 Co-Lead

MARTIN YARMUCH (MGH)
TA1 Co-Lead

REBECCA SANDLIN (MGH)
TA2 Co-Lead

BORIS RUBINSKY (UC Berkeley)
TA2 Co-Lead

GUILLERMO AGUILAR (TAMU)
TA3 Co-Lead

ZONGHU HAN (UMN)
TA3 Co-Lead

BERK USTA (MHG)
Cell Lead

KEVIN HEALY (UC Berkeley)
Tissues and MPS Lead

BASAK UYGUN (MGH)
Organ Co-Lead

NIKOLAS ZUCKOWICZ (UMN)
Organism Lead


Convergent Research Faculty

JOHN BISCHOF

ERIK FINGER

RHONDA FRANKLIN

BETHANY STADLER

PAUL IAZZIO

CHRIS HOGAN

MICHAEL McALPINE

BHAIRAB SINGH

BRENDA OGLE

SUHASA KODANDARAMAIAH

AMANDA NEISCH

ALPTEKIN AKSAN

TIM PRUETT

 

MEHMET TONER

KORKUT UYGUN

MARTIN YARMUSH

REBECCA SANDLIN

SHANNON TESSIER

BASKA UYGUN

BERK USTA

DANIEL IRIMIA

ASLIHAN GOKALTUN

 

GUILLERMO AGUILAR

MATTHEW POWELL-PALM

ARUL JAYARAMAN

JEFF TOMBERLIN

ELAHEH RAHBAR

 

LORENZO MANGOLINI

YADONG YIN

JIN NAM

 

BORIS RUBINSKY

KEVIN HEALY

CHRIS DAMES

 

YOED RABIN

LEVENT BURAK KARA

 

Convergent Research Site Expertise

  • - Heat transfer
    - Electromagnetic technologies
    - Nanowarming
    - Organ and tissue transplantation
    - Aerosols
    - Nucleation and crystallization
    - Robotics
    - Aquatic species cryopreservation
    - Insects cryopreservation

  • - Cryobiology
    - Bio- cryopreservation
    - Perfusion
    - Organ and tissue transplantation
    - Tissue and organ engineering
    - Cryoprotectant optimization
    - Microfluidics
    - Metabolomics
    - CPA optimization and high throughput
    - Insects cryopreservation 

  • - Opto-electronics
    - Laser nanowarming
    - Thermodynamics
    - Isochoric
    - Molecular systems biotechnology in inflammatory diseases
    - Metabolism
    - Conservation biology.

  • - Materials science
    - Nanofabrication
    - Magnetic and plasmonic nanoparticles
    - Tissue engineering
    - Mechanobiology 
    - Cryosupply chain

  • - Cryobiology
    - Thermodynamics
    - Isochoric cryopreservation
    - 3D printing
    - Micro-physiological systems
    - Thermal properties

  • - Computational modeling in cryobiology
    - Cryomedicine
    - Machine learning
    - Organ modeling
    - CPA optimization and high throughput